生态室研究员简介

贺超良 博士

研究员 博士生导师 高分子化学专业

生物高分子研究组

办公室：合成楼123房间

电  话：+86-431-85262901

E-mail：clhe@ciac.ac.cn

教育和工作经历

1997.09–2001.07，华东理工大学，应用化学，工学学士学位

2001.09–2007.01，中科院长春应用化学研究所，高分子物理与化学，理学博士学位

2007.03–2008.08，韩国成均馆大学，博士后

2008.11–2010.08，加拿大渥太华大学，博士后

2010.09-2015.12，中科院长春应用化学研究所，副研究员

2016.01至今，中科院长春应用化学研究所，研究员，优青 

学术任职

《Science China Technological Sciences》，青年编委
《中国科学：技术科学》，青年编委 

获奖及荣誉

1、2013年入选中国科学院青年创新促进会（2017年入选优秀会员）

2、2016年获得国家自然科学基金“优秀青年科学基金”

研究领域及现状

主要从事生物医用高分子水凝胶的研究开发。作为项目负责人先后承担国家自然科学基金5项（包括优秀青年基金、面上和青年基金）。近年来以第一作者或通讯作者发表论文50余篇，申请专利23项，其中授权17项。专业方向为“高分子化学与物理”和“生物化工”。现担任《中国科学：技术科学》和《Science China Technological Sciences》青年编委。2016年获得国家优秀青年科学基金。

主要代表性论文

1. Zhen Zhang, Chaoliang He*, Yan Rong, Hui Ren, Tianran Wang, Zheng Zou, Xuesi Chen*, A fast and versatile cross-linking strategy via o-phthalaldehyde condensation for mechanically strengthened and functional hydrogels, National Science Review, 7(2020), DOI: 10.1093/nsr/nwaa128.

2. Yuhao Zhou, Liang Liu, Yue Cao, Shuangjiang Yu, Chaoliang He*, Xuesi Chen*, A nanocomposite vehicle based on metal-organic framework nanoparticle incorporated biodegradable microspheres for enhanced oral insulin delivery, ACS Applied Materials & Interfaces, 12(2020), 22581-22592.

3. Shuangjiang Yu, Chao Wang, Jicheng Yu, Jinqiang Wang, Yue Lu, Yuqi Zhang, Xudong Zhang, Quanyin Hu, Wujin Sun, Chaoliang He*, Xuesi Chen*, Zhen Gu*, Injectable bioresponsive gel depot for enhanced immune checkpoint blockade, Advanced Materials, 30(2018), 1801527.

4. Qiang Lv, Chaoliang He*, Fenli Quan, Shuangjiang Yu, Xuesi Chen, DOX/IL-2/IFN-γ co-loaded thermo-sensitive polypeptide hydrogel for efficient melanoma treatment, Bioactive Materials 3(2018), 118-128.

5. Qinghua Xu, Zhen Zhang, Chunsheng Xiao, Chaoliang He*, Xuesi Chen*, Injectable polypeptide hydrogel as biomimetic scaffolds with tunable bioactivity and controllable cell adhesion, Biomacromolecules, 18(2017) , 1411-1418.

6. Chaoliang He, Zhaohui Tang, Huayu Tian, Xuesi Chen*, Co-delivery of chemotherapeutics and proteins for synergistic therapy, Advanced Drug Delivery Reviews, 98(2016), 64-76.

7. Xilong Wu, Chaoliang He*, Yundi Wu, Xuesi Chen*, Synergistic therapeuticeffects of Schiff's base cross-linked injectable hydrogels for local co-delivery of metformin and 5-fluorouracil in a mouse colon carcinoma model, Biomaterials, 75(2016), 148-162.

8. Qinghua Xu, Chaoliang He*, Zhen Zhang, Kaixuan Ren, Xuesi Chen*, Injectable, biomolecule-responsive polypeptide hydrogels for cell encapsulation and facile cell recovery through triggered degradation, ACS Applied Materials & Interfaces, 8(2016), 30692-30702.

9. Qinghua Xu, Chaoliang He*, Chunsheng Xiao, Xuesi Chen*. Reactive oxygen species (ROS) responsive polymers for biomedical applications. Macromolecular Bioscience 2016, 16(5), 635-646.

10. Kaixuan Ren, Chaoliang He*, Chunsheng Xiao, Gao Li*, Xuesi Chen, Injectable glycopolypeptide hydrogels as biomimetic scaffolds for cartilage tissue engineering, Biomaterials, 51(2015), 238-249.