生态室副高级职员

姓  名

孙海

学 位

硕士

职  务

 无

职 称

副研究员

研究组

生物高分子研究组

办公室

聚合基地207

电  话

0431-85262111

E-mail

sunhai@ciac.ac.cn

2000.09-2009.07      吉林大学化学科学学院，学士学位（2004，应用化学）、博士学位（2009，有机化学）

2009.07-2011.07      中科院长春应用化学研究所，博士后

2011.07-至今            中科院长春应用化学研究所，助理研究员、副研究员（2015）

生物可降解医用高分子材料的研究及应用开发。

围绕聚乳酸类医用高分子材料的合成、纯化、表征和规模化生产开展科研工作，并利用开发的原材料研发多种可吸收医疗器械，解决临床上急需解决的技术难题。

1.  Hai Sun, Di Li, Jianxun Ding, Zhaohui Tang, Ying Zhang, Weiguo Xu, Xiuli Zhuang, Xuesi Chen. Polymeric topology and composition constrained polyether–polyester micelles for directional antitumor drug delivery. Acta Biomaterialia. 2013.

2.  Di Li，Jian Xun Ding，Zhao Hui Tang，Hai Sun，Xiu Li Zhuang，Jing Zhe Xu，Xue Si Chen. In vitro evaluation of anticancer nanomedicines based on doxorubicin and amphiphilic Y-shaped copolymers. International Journal of Nanomedicine, 2012, 7, 2687–2697.

3.  Mingqiang Li, Wantong Song, Zhaohui Tang, Shixian Lv, Lin Lin, Hai Sun, Quanshun Li,Yan Yang, Hua Hong, and Xuesi Chen. Nanoscaled Poly(L？glutamic acid)/Doxorubicin-Amphiphile Complex as pH-responsive Drug Delivery System for Effective Treatment of Nonsmall Cell Lung Cancer. ACS Appl. Mater. Interfaces 2013, 5, 1781？1792.

4.  Yue Huang, Zhaohui Tang, Xuefei Zhang, Haiyang Yu, Hai Sun, Xuan Pang, and Xuesi Chen. pH-Triggered Charge-Reversal Polypeptide Nanoparticles for Cisplatin Delivery: Preparation and In Vitro Evaluation. Biomacromolecules, 2013, 14, 2023？2032.

5.  Mingqiang Li, Zhaohui Tang, Hai Sun, Jianxun Ding, Wantong Song and Xuesi Chen. pH and reduction dual-responsive nanogel cross-linked by quaternization reaction for enhanced cellular internalization and intracellular drug delivery. Polym. Chem., 2013, 4, 1199–1207.

6.  Lv S, Li M, Tang Z, Song W, Sun H, Liu H, Chen X. Doxorubicin-loaded amphiphilic polypeptide-based nanoparticles as an efficient drug delivery system for cancer therapy. Acta Biomaterialia 2013;9:9330-42.